Assessment of global cerebral blood flow perfusion in fetuses with congenital heart diseases by three-dimensional ;power Doppler ultrasound
10.3760/cma.j.issn.1004-4477.2015.08.006
- VernacularTitle:三维能量多普勒超声检测先天性心脏病胎儿全脑血流灌注的研究
- Author:
Shi ZENG
;
Qichang ZHOU
;
Jiawei ZHOU
;
Ganqiong XU
;
Qinghai PENG
;
Xiaofang WANG
;
Rongsheng ZHANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Heart defects,congenital;
Cerebrovascular circulation
- From:
Chinese Journal of Ultrasonography
2015;(8):661-664
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate global cerebral blood flow perfusion in fetuses with congenital heart disease (CHD)by three-dimensional power Doppler ultrasound (3D PD).Methods The vascular index (VI),flow index (FI)and vascular/flow index (VFI)in the global cerebral were prospectively compared in 1 12 fetuses with CHD and 1 12 normal fetuses using 3D PD.Correlations between the 3D PD indices and neurodevelopment scores were assessed.Results Compared with the controls,the VI,FI and VFI of the global brain were significantly increased in fetuses with hypoplastic left heart syndrome (HLHS) and left sided obstructive lesions (LSOLs)(P <0.001).The mean psychomotor development index (PDI) and mental development index (MDI)scores were significantly lower than normal (P < 0.001 ).FI was positively correlated with PDI (r =0.342,P =0.029)and MDI (r =0.339,P =0.030).Conclusions Global cerebral blood flow perfusion was significantly increased in most fetuses with CHD and had association with neurodevelopment scores.3D PD ultrasound might help to identify cases of brain vasodilatation earlier and inform parental counseling.
