Value of contrast-enhanced ultrasound and enhancement MRI in differetial diagnosis of the orbital neoplasms
10.3760/cma.j.issn.1004-4477.2015.08.019
- VernacularTitle:超声造影与增强 MRI 在眼眶肿瘤中的应用价值
- Author:
Peng LI
;
Ying CHEN
;
Li WU
;
Wenwei CHEN
;
Xingyue HUANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Orbital neoplasms;
Magnetic resonance imaging
- From:
Chinese Journal of Ultrasonography
2015;(8):705-709
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the ability of contrast-enhanced ultrasonography (CEUS ) compared to enhanced MRI scan in differential diagnosis of benign and malign tumor of orbit.Methods CEUS and enhanced MRI was performed in 74 patients with tumor of orbit.These patients were divided into two groups:benign and malignant tumor depended on histological diagnosis.The results were analysed with SonoLiver software.The coincidence rate of diagnosis and enhancement intensity among CEUS,MRI and CEUS+ MRI were compared and the quantitative parameters of CEUS were analysed.Results (1 )The diagnostic accordance rate of benign group by three methods were 90.0%,80.0% and 96.0% respectively, there was statistical difference for diagnostic coincidence rate between the MRI and CEUS+ MRI(P <0.05).The diagnostic accordance rate of malignant group by the above three methods were 75.0%,79.2%and 95.8% respectively,there was no statistical difference for diagnostic coincidence rate between the three methods(all P > 0.05 ).(2 )The enhancement intensity of CEUS was different between benign and malignant groups (P <0.05).There was no statistical difference between benign and malignant groups by MRI method (P >0.05).(3)The parameters of tumor imaging obtained time intensity curve(TIC):rise time (RT),half elution time and time to peaking (TTP)were significantly different between benign and malignant groups(P <0.05).While there was no significant difference of parameters as mean transit time (mTT)and arrived time (AT)(P >0.05).Conclusions CEUS had higher diagnostic accuracy than MRI in benign orbital tumor.The contrast enhancement intensity and time-intensity curves provide valuable diagnostic information for differential diagnosis of benign and malignant orbital tumor.
