A Case of T-cell Lymphoblastic Lymphoma Involving the Skin.
- Author:
Min Jung WOO
1
;
Sung Woo LEE
;
Sang Won KIM
;
Ghil Suk YOON
Author Information
1. Department of Dermatology, Catholic University of Daegu School of Medicine, Daegu, Korea.
- Publication Type:Case Report
- Keywords:
T-cell lymphoblastic lymphoma;
Scaly patches
- MeSH:
Chromatin;
Cytoplasm;
Dermis;
Drug Therapy, Combination;
Female;
Follow-Up Studies;
Humans;
Leukemia;
Lymphocytes;
Lymphoma, Non-Hodgkin;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*;
Skin*;
T-Lymphocytes*;
Young Adult
- From:Korean Journal of Dermatology
2003;41(2):227-231
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lymphoblastic lymphoma(LBL) is non-Hodgkin's lymphoma with a high tendency of rapid progression to acute leukemia, but cutaneous infiltration is rare. Cutaneous lesions in LBL were largely red papules and nodules. We herein report a case of 24-year-old woman with T-cell LBL(TLBL) involving the skin. The lesions revealed 1~3 cm-sized, multiple confluent scaly patches on her face and back, and subsided about 4 weeks later during the period of follow-up and combination chemotherapy. Histologically there were perivascular, periadnexal and perineural infiltrates of medium-sized lymphoid cells in mid to deep dermis. The neoplastic cells had scant cytoplasm, very fine chromatin, and inconspicuous nucleoli and expressed CD5, CD45, CD45RO and TdT.
