Cardiovascular protective effects of glucagon-like peptide-1 agents in patients with type 2 diabetes

VernacularTitle:胰升糖素样肽1药物对2型糖尿病患者的心血管保护效应
Author: Jing KE ; Rui WEI ; Tianpei HONG
Publication Type:Journal Article
Keywords: Glucagon-like peptide-1; Diabetes mellitus,type 2; Cardiovascular disease
From: Chinese Journal of Endocrinology and Metabolism 2015;(9):812-815
CountryChina
Language:Chinese
Abstract: [Summary] Glucagon-like peptide-1 ( GLP-1 ) agents play important roles in glycemic control in type 2 diabetes. Moreover, these agents also show various protective effects on cardiovascular system. GLP-1 agents improve vascular endothelial function, ameliorate the risk factors of cardiovascular disease including obesity, hyperglycemia, dyslipidemia and hypertension, delay the occurrence and progression of atherosclerosis, and protect against cardiac ischemia-reperfusion injury and heart failure. Therefore, GLP-1 agents may have beneficial effects on cardiovascular diseases at different stages and in multiple aspects.