Comparative analysis of predictive value of different inflammatory markers for the severity of community-acquired pneumonia in adult and elderly patients
10.3969/j.issn.1673-4130.2015.19.014
- VernacularTitle:不同指标对成年及老年社区获得性肺炎严重程度预测价值的对比分析
- Author:
Zongli LI
;
Changhong ZHANG
;
Xiaorong LI
;
Zuoqing ZHANG
- Publication Type:Journal Article
- Keywords:
community-acquired pneumonia;
procalcitonin;
C reactive protein;
white blood cell;
predictive value
- From:
International Journal of Laboratory Medicine
2015;(19):2808-2809
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the predictive value of procalcitonin (PCT),C-reactive protein (CRP)and white blood cell (WBC)for the severity of community-acquired pneumonia(CAP)in adult and elderly patients.Methods A total of 1 12 hospitalized patients with community acquired pneumonia from May 2013 to September 2014 were selected,and they were divided into the adult group(n=50)and the elderly group (n =62).The PCT,CRP and WBC levels in patients with severe and non-severe pneumonia were compared,and the correlation between those inflammatory markers and pneumonia severity index (PSI),British Thoracic Soci-ety CURB-65 Score(CRUB-65)were analyzed in each age group.Results PCT and CRP levels,PSI and CURB-65 scores in adult and elderly patients with severe pneumonia were higher than those in patients with non-severe pneumonia of corresponding age group (P < 0.05 ).Moreover,PCT had significant positive correlation with PSI and CURB-65 scores in the elderly group (P <0.05).But no correlation were found between the two kinds of scores and PCT in adult group as well as CRP,WBC in the two age group(P >0.05).Conclusion PCT and CRP might be useful markers to evaluate the severity of CAP,and PCT has a higher pre-dictive value in elderly patients with CAP.