Research on Chinese medicine progress and model preparation of myocardial ischemia-reperfusion injury
- VernacularTitle:心肌缺血再灌注损伤的中医药研究进展及其模型的制备
- Author:
Lu CHEN
;
Weiwei LI
;
Chunhui LIU
- Publication Type:Journal Article
- Keywords:
myocardial ischemia-reperfusion;
animal models;
improve
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(9):174-176
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic cardiomyopathy (ICM) is due to coronary atherosclerosis cause long-term myocardial ischemia, make myocardial fibrosis diffuse, produce similar clinical syndrome like idiopathic dilated cardiomyopathy, which is one of a common clinical disease and causes increasing hazards to human health.Timely recovery of blood perfusion and coronary artery recanalization is one of the effective methods of treatment.However, it brings new damage while tissues and organs receive reperfusion, which is myocardial ischemia-reperfusion injury.In this paper, the current research progress in medicine myocardial ischemia-reperfusion injury and how to build a simple and efficient experimental animal models to mimic human myocardial ischemia-reperfusion injury were reviewed.
