Effect of appling small molecule heparin calcium on long-term renal damage of patients with allergic purpura by Meta analysis
- VernacularTitle:应用小分子肝素钙对过敏性紫癜并发远期肾损害干预效果的Meta分析
- Author:
Zhanru YIN
- Publication Type:Journal Article
- Keywords:
small dose molecular heparin calcic;
Henoch-Schonlein purpura;
kidney damage;
intervention;
Meta analysis
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(9):177-179
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate small molecule heparin allergic purpura complicated by long-term kidney damage intervention by Meta analysis.Methods Databases of CNKI,Wanfang,VIP,CBM and Cochrane Library were searched,hand searching as an auxiliary, included studies were assessed by quality of analysis, Meta-analysis was conducted by Stata12.1 software line.Results 4 articles were included in randomized controlled clinical trials (randomized controlled trials, RCT), a sample of 670 cases, 333 cases of small molecule heparin calcium treatment group (37 cases of renal damage has occurred), 337 cases of control group (44 cases of renal damage has occurred), no difference between the 2 groups (RR=0.89, 95% CI:0.59-1.34, P=0.578).Conclusion The early application of small molecular weight heparin calcium can not prevent kidney damage, it needs to do in-depth research by multi-center, large-scale RCT.
