Progress of research on gabapentin for refractory chronic cough
- VernacularTitle:加巴喷丁用于难治性慢性咳嗽治疗的研究进展
- Author:
Chunyan QIAN
;
Huizhu SONG
;
Xiaojun CAI
;
Shourong LU
;
Hao WEN
- Publication Type:Journal Article
- Keywords:
gabapentin;
chronic cough;
sensory neuropathy
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(9):180-182
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review advance of gabapentin in treatment of refractory chronic cough, and to provide evidence for its clinical usage and further study.The original articles referring to gabapentin’ s effect on sensory neuropathy such as refractory chronic cough, which were retrieved from CNKI, Wanfang Medical Network, as well as PubMed over the last 15 years, were reviewed.The safety, efficacy and its mechanism of gabapentin were sorted, generalized and analyzed.Gabapentin appears to be effective and safe in the treatment of sensory neuropathic disorder such as refractory chronic cough, and its effective treatment results may come ture through improving central sensitization, which indicates the drug has new clinical application value.Relevant clinical trials investigating its efficacy and safety profile in the treatment of cough are limited and further research are needed.
