Spray Drying Process of Anshen Bumian Granules
10.3870/j.issn.1004-0781.2015.10.019
- VernacularTitle:安神补眠颗粒喷雾干燥工艺?
- Author:
Fei HAN
;
Honghu ZENG
;
Jie ZHANG
;
Hanlin XU
;
Ming YANG
;
Xiaojian LUO
- Publication Type:Journal Article
- Keywords:
Anshen bumian granules;
Spray drying;
Orthogonal experiment;
Moisture content;
Berberine hydrochloride
- From:
Herald of Medicine
2015;(10):1332-1335
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize spray drying process of Anshen bumian granules. Methods By using orthogonal design method, moisture content, powder rate and berberine hydrochloride content were indexes, and optimum technological conditions were determined. Results Proportion of microcrystalline cellulose, lactose and maltodextrin was 2??1??2. The extract was fed in at 6%. Optimum feeding in/out temperature for spray drying is 145 ℃ /85 ℃, liquid velocity was 30 mL??min-1 , and relative density of extract was 1. 15. Conclusion The process is reasonable and practical, has strong stability and good controllability, and it provides a basis for industrialized production.
