Research Progress on Animal Modeling Methods and Model Evaluation of Spleen-yang Deficiency
10.11842/wst.2015.08.023
- VernacularTitle:脾阳虚证动物模型造模方法与模型评价的研究进展
- Author:
Qin LI
;
Huiyong ZHANG
;
Tianshi WU
;
Zhe ZHANG
;
Guanlin YANG
- Publication Type:Journal Article
- Keywords:
Spleen-yang deficiency;
rhubarb;
improper diet;
cold-dampness impairing spleen;
reserpine
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2015;(8):1721-1728
- CountryChina
- Language:Chinese
-
Abstract:
The paper was aimed to review the modeling methods of spleen-yang deficiency, which can be classified into imitating traditional Chinese medicine (TCM) etiology methods and modern medicine methods. At present, methods of modeling were not generally accepted and the main presented problems were as follows. Modern medicine methods did not conformed to the rules of TCM etiology and pathogenesis. The evaluation of yang deficiency models was not accurate. Some modeling methods can lead to other diseases at the same time. The names of spleen deficiency model were not unified. It was difficult to distinguish the modeling methods of spleen-yang deficiency and spleen-qi deficiency, and etc. Model evaluation of spleen-yang deficiency was various. However, the domestic standard evaluation system had not been formed. The main model evaluation problems were as follows. Macro symptoms of the model lacked of objective and quantitative evaluation. It lacked of evaluation indexes of pulse and tongue with TCM characteristics. The disproof of prescription selection was not unified. Similar syndromes had not been ruled out. The microscopic indexes were fragmented, and etc. This paper reviewed on animal modeling methods of spleen-yang deficiency.
