Correlation of interleukin-6 and C-reactive protien levels with left atrial thrombus and severe spontaneous echocontrast in atrial fibrillation patients
10.11958/j.issn.0253-9896.2015.08.019
- VernacularTitle:IL-6和C反应蛋白与房颤患者左房血栓和重度左房超声自发性显影的关系
- Author:
Jinguo ZHENG
;
Yonghui HE
;
Xintao DENG
;
Guiliang SHI
;
Min PAN
- Publication Type:Journal Article
- Keywords:
interleukin-6;
C-reactive protien;
atrial fibrillation;
left atrial thombus
- From:
Tianjin Medical Journal
2015;(8):899-901
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of serum interleukin-6 (IL-6) and C-reactive protien (CRP) lev?els with left atrial thrombus and severe spontaneous echocontrast (SEC) in patients with atrial fibrillation (AF). Methods A case-control study of patients with atrial fibrillation (n=76) was carried out. All patients were divided into control group (n=45) and study group (n=31) according to their conventional echocardiography performance. Serum IL-6 and CRP were exam?ined in both groups. Results The levels of serum IL-6 in patients with thrombus and severe SEC were (324.13±42.86) ng/L and (332.29±53.17) ng/L, respectivly which is higher than that in patient without thrombus or without severe SEC (108.75± 25.43) ng/L and (93.59 ± 27.82) ng/L respectively. In parallel, CRP levels in patients of thrombus and severe SEC were (66.97 ± 17.65) mg/L and (71.81 ± 20.19) mg/L respectively which is higher than that in patients without thrombus or without severe SEC (17.28±6.52) mg/L and (16.76±8.73) mg/L respectively. All differences were of statistically significant(P<0.05). Conclusion Increase of serum IL-6 and CRP as well as high systemic inflammatory state correlate with left atrial thombus and severe SEC in patients with AF.
