Pathogen profile of bloodstream infections in low birth weight preterm infants:a report of 95 cases
- VernacularTitle:早产低体重儿血流感染95例病原学分析
- Author:
Xiaohua TANG
;
Xicai TANG
;
Weiqin YANG
;
Jiezhen HUANG
;
Zihao OU
- Publication Type:Journal Article
- Keywords:
low birth weight preterm infant;
bloodstream infection;
antibiotic resistance
- From:
Chinese Journal of Infection and Chemotherapy
2015;(5):439-442
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the etiology and antibiotic resistance of bloodstream infections in low birth weight preterm infants .Methods A total of 95 cases of bloodstream infections in low birth weight preterm infants were treated in our hospital from January 2011 to April 2014 .The clinical data of these patients were analyzed retrospectively .Results A total of 96 pathogens were isolated ,including 57 strains of gram‐negative bacilli ,38 strains of gram‐positive cocci ,and 1 strains of Trichosporon asahii .The most frequently isolated pathogens were Klebsiella pneumoniae (40 strains)and coagulase‐negative Staphylococcus(31 strains).All gram‐negative bacilli were sensitive to carbapenems such as imipenem and panipenem . Streptococcus isolates were sensitive to most antibiotics .Most Staphylococcus isolates were methicillin‐resistant ,which were highly resistant to common antibiotics but all sensitive to linezolid , vancomycin and teicoplanin . Conclusions The most important pathogens responsible for bloodstream infections in low birth weight preterm infants in our hospital are K lebsiella pneumoniae and coagulase‐negative Staphylococcus . Early identification of responsible pathogen and rational antimicrobial therapy are critical for good prognosis of bloodstream infections in low birth weight preterm infants .
