Clinical distribution and changing resistant pattern of Enterobacter cloacae
- VernacularTitle:阴沟肠杆菌的临床分布及耐药性变迁
- Author:
Zhaolian LU
;
Yanwen GONG
;
Lian XUE
;
Chengjin HU
- Publication Type:Journal Article
- Keywords:
Enterobacter cloacae;
distribution;
bacterial resistance
- From:
Chinese Journal of Infection and Chemotherapy
2015;(5):459-461
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and resistant pattern of Enterobacter cloacae to antimicrobial agents for reasonable use of antibiotics .Methods E .cloacae strains were isolated from patients from January 2009 to December 2013 .The strains were identified by VITEK‐2 Compact System of BioMerieux and tested for antimicrobial susceptibility by Kirby‐Bauer disk diffusion method .The results were analyzed .Results A total of 397 nonduplicate E .cloacae strains were isolated during 5 years ,accounting for 5 % of the total gram‐negative isolates . The strains were mainly isolated from sputum (48 .9% ) , followed by secretions (30 .5% )and urine (7 .3% ) .The percentage of E .cloacae strains resistant to all the antibiotics tested was on decline except carbapenems ,cefoxitin and amoxicillin‐clavulanic acid .Carbapenems were relatively more active against E .cloacae strains .The E .cloacae strains showed higher resistance rate toβ‐lactams .Conclusions It is necessary to strengthen the monitoring of clinical isolates to guide rational use of antimicrobial agents .
