Observation of Curative Effect ofHejie Fenxiao Decoction on Acute Kidney Injury
10.3969/j.issn.1005-5304.2015.10.010
- VernacularTitle:和解分消汤治疗急性肾损伤疗效观察
- Author:
Gaihua ZHANG
;
Shen LI
;
Mengqi YOU
;
Qiuhua HUANG
;
Yu ZHAO
;
Li WANG
;
Xiangrong RAO
;
Wensheng QI
- Publication Type:Journal Article
- Keywords:
Hejie Fenxiao Decoction;
acute kidney injury;
curative effect
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(10):31-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy ofHejie Fenxiao Decoction on damp-heat patients with acute kidney injury (AKI).Methods Totally 68 patients were divided into the control group and the treatment group according to the patients’ willings. Both groups were given treatment, such as elimination of the incentives and symptomatic treatment. Besides, patients of the treatment group acceptedHejie Fenxiao Decoction for 30 days. The changes of renal function indexes, such as serum creatinine (SCr), blood urine nitrogen (BUN), uric acid (UA), albumin (ALB) and integral of TCM syndrome, were observed, and recovery ratio and clinical endpoints were compared.Results SCr and eGFR of both group were improved on day 14 (P<0.05). After treatment, the renal function recovery ratio and renal replacement ratio in the two groups showed obvious differences (P<0.05);although survival rate of treatment group was higher than control group, it showed no statistical significance (P>0.05);clinical endpoints analysis of the two groups showed statistical significance (P<0.05). The difference of integrals of TCM syndrome between the two groups showed statistical significance (P<0.05) on day 14.ConclusionHejie Fenxiao Decoction combined with basic regular Western medicine can better improve the clinical symptom, recover the renal function, and decrease the rate of renal replacement and death of AKI damp-heat patients.
