Research Progress of Artemisinins-based Antimalarial Agents
10.3969/j.issn.1005-5304.2015.10.039
- VernacularTitle:青蒿素类抗疟制剂研究概述
- Author:
Shuo SHEN
;
Shuzhi LIU
;
Maobo DU
- Publication Type:Journal Article
- Keywords:
artemisinin;
malaria;
antimalarial agent;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(10):125-128
- CountryChina
- Language:Chinese
-
Abstract:
Artemisinin is the antimalarial active ingredient, which is discovered by Chinese scientists in 1970s. The chemical structure of artemisinin is modified or altered to obtain a series of analogues to satisfy the medication requirements. According to the physicochemical properties of medicines and actual clinical necessities, the preparations of artemisinins are developed and the common preparations include tablet, suppository, injection, etc.. With the developing of technology, researchers have conducted a large number of studies on the artemisinins nanoparticles injection, transdermal drug delivery systems, mucosal drug delivery systems and etc. This article systematically collected and discussed the recent studies on the antimalarial preparations of artemisinins in line with different administration routes.