Advances of immunotherapy in lymphoma
10.3760/cma.j.issn.1009-9921.2015.10.001
- VernacularTitle:淋巴瘤的免疫治疗进展
- Author:
Bo JIA
;
Yuankai SHI
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Immunotherapy;
Immunomodulation;
Immune checkpoint
- From:
Journal of Leukemia & Lymphoma
2015;24(10):577-579
- CountryChina
- Language:Chinese
-
Abstract:
Over the past years, the incidence of lymphoma has been increasing, which has become one of the most common cancers around the world.The survival of lymphoma patients has been significantly improved due to advances of therapeutic methods such as new chemotherapy regimens, monoclonal antibodies and small molecular targeted drugs.However, the number of patients with relapsed/refractory lymphoma still account for a large proportion.It is of great significance to find new ways to treat these patients.Cellular immunotherapy could kill tumor cells by causing specific and effective antitumor immune response.Remarkable advances have been made in immunotherapy, such as adoptive immunotherapy, immune checkpoint inhibitors and immunomodulation therapy, for relapsed/refractory lymphoma patients, which will gradually open a new era in the treatment of lymphoma.