Effects oftwo kinds of crystals priming on levels of glucose and lactic acidin pediatrics withcardiopul-monary bypass during congenital heart surgery
10.3969/j.issn.1006-5725.2015.15.022
- VernacularTitle:两种晶体预充液对儿童心肺转流术中血糖及乳酸的影响
- Author:
Jie LV
;
Hong GAO
;
Wei OU
;
Xiaohua ZOU
;
Li TAN
;
Qiang TIAN
- Publication Type:Journal Article
- Keywords:
Cardiopulmonary bypass;
Priming solution;
Lactic acid;
Blood glucose
- From:
The Journal of Practical Medicine
2015;31(15):2480-2482
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect of Acetate Sodium Potassium Magnesium Calcium and lactate ringers′ as priming solution in pediatrics with cardiopulmonary bypass (CPB) during congenital heart surgery. Methods Sixty children, aged 1-6 years, weighting 8 to 20 kg, with ASA Ⅱ to Ⅲ class and with ventricular or atrial septal defect elective , received heart surgery with CPB. They were randomly divided into two groups: the lactate ringers′ group (R) and the sodium acetate, potassium, magnesium and calcium glucose injection pre-filled group (L). Levels of artery blood gas, lactic, gluclose, electrolytes were detected at the time points of induction of anesthesia (T1), aortic cross damping (T2), stopping before (T3), and closing chest later (T4). Results Levels of the blood glucose and lactic acid in the two groups post-CPB were increased (P <0.01) at T2 and T3. Lactic acid level in group L was lower than that in group R (P < 0.05), and the blood glucose level in group L was higher than that in group R (P < 0.01). No significant difference was found in the lactic acid and blood glucose post-closing chestbetween the two groups (P > 0.05). Conclusion Sodium, potassium , magnesium , calcium and glucose injection as children CPB priming crystalloid fluid could provide energy substrate, reduce lactic acid concentration, with little effect on electrolyte and blood gas.
