Effects of different sedation depth of propofol on cerebral oxygen metabolism of the elder patients during anesthesia
10.3969/j.issn.1006-5725.2015.15.045
- VernacularTitle:异丙酚不同镇静深度对全麻老年患者脑氧代谢的影响
- Author:
Rui GUO
;
Wanwen HE
;
Lixun WANG
;
Hui LI
;
Youli CHEN
;
Jianbin LI
- Publication Type:Journal Article
- Keywords:
Propofol;
Elder patient;
CERO2
- From:
The Journal of Practical Medicine
2015;31(15):2551-2553
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of propofol with different sedation depth on CERO 2 of elder patientsduring anesthesia. Method 60 case patients under cholecystotomywith laparoscope, ASA IorⅡgrading, 65-75 year old , 45-75 kg , were randomly divided into 3 groups ( n = 20 ) and were divided into group A (3 μg/mL), group B (4 μg/mL), group, C (5 μg/mL), according to TCI of propofol. TCI in different groups were modified after gereral anesthesia. Bloodgas was analyzed by blood samples taken from radial artery and Sjv ball, Da-jvO2 and CERO2 were calculated. Results The Da-jvO2 and CERO2 of group B and C were significantly lower thanthose of group A at T2,3, while CjvO2 were significantly higher thangroup A (P < 0.05). The Da-jvO2 and CERO2 of group B and C werenot significantly different (P > 0.05); NI value of group A in T1-3 was significantly higher thangroup B (P < 0.05), while. NI value of group B in T1-3 was significantly higher thangroup C (P < 0.05). Conclusion Propofol TCI 4 μg/mL, can improve cerebral oxygen metabolism of elder patients and decrease CERO2.
