Significance of fiberoptic bronchoscopic brush cytology in lung carcinoma diagnosis
10.3760/cma.j.issn.1008-6315.2015.08.020
- VernacularTitle:纤维支气管镜刷片细胞病理学在肺癌诊断及分型中的意义
- Author:
Yong CHEN
;
Yanhua CHANG
;
Qing GUO
;
Ying CAI
;
Rongchao SUN
- Publication Type:Journal Article
- Keywords:
Fiberoptic bronchoscopic brushing cells;
Cytology;
Lung carcinomas
- From:
Clinical Medicine of China
2015;31(8):737-739
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the significance of fiberoptic bronchoscopic brush cytology in the diagnosis and histological classification of lung carcinoma.Methods Data of 309 patients with lung carcinoma were retrospectively analyzed.Both bronchoscopic cytology and histology diagnosis were available.The positive rate of bronchoscopic cytology and tissue biopsy were calculated respectively.The classification accuracy of cytological diagnosis for lung carcinoma was evaluated.In tissue biopsy standard,evaluated the significance of bronchoscopic cytology in diagnosis and histological diagnosis.Results The positive rate of bronchoscopic cytology and tissue biopsy were 86.1％ (266/309) and 83.8％ (259/309),respectively.Bronchoscopic cytology combined with bronchial biopsy could obviously improve the positive rate to 94.2％ (291/309) in lung carcinoma diagnosis.Taking the tissue biopsy histological type as a standard,the cytotyping accuracy for brush method was 85.1％(74/87) in squamous carcinoma,82.4％(108/131) in adenocarcinoma and 100％(11/11) in small cell carcinoma for higher.However,the accuracy in diagnosing poorly differentiated carcinomas was only 12.2％ (5/ 41).Conclusion Fiberoptic bronchoscopic brush cytology plays an stable and important role in diagnosing lung carcinomas and histological type determination.However,it has limited use in diagnosing poorly differentiated carcinomas.
