Research progress on hepatic ischemia/reperfusion injury
10.3760/cma.j.issn.1673-4203.2015.10.021
- VernacularTitle:肝脏缺血再灌注损伤发生机制的研究进展
- Author:
Yibao DU
;
Bo DONG
;
Chengguang YANG
;
Wei JIN
;
Peng SUN
- Publication Type:Journal Article
- Keywords:
Liver;
Reperfusion injury;
Signaling pathway;
Research
- From:
International Journal of Surgery
2015;42(10):713-716
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic ischemia/reperfusion injury is an important restricting factor of clinical liver resection and liver transplantation.When the liver is transiently deprived of blood followed by repeffusion,a large number of various mediators are released that can lead to cellular and,eventually,organ dysfunction.This review summarizes the pathogenesis and the protection mechanisms of hepatic ischemia/reperfusion injury.