Clinical efficiency of Esomeprazole and Omeprazole triple therapies on gastric ulcer patients complicated with type 2 diabetes mellitus
10.3760/cma.j.issn.1008-6315.2015.05.018
- VernacularTitle:埃索美拉唑与奥美拉唑三联疗法在2型糖尿病合并胃溃疡中的效果比较
- Author:
Hui SUN
;
Tao SUN
;
Yi LI
- Publication Type:Journal Article
- Keywords:
Esomeprazole;
Omeprazole;
Gastric ulcer;
Ddiabetes mellitus;
Amoxicillin and clavulanate potassium dispersible tablets;
Clarithromycin
- From:
Clinical Medicine of China
2015;31(5):437-439
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy of esomeprazole or omeprazole triple therapies on gastric ulcer patients complicated with type 2 diabetes mellitus.Methods Seventy-five patients with Hprelated gastric ulcer and type 2 diabetes mellitus were enrolled and were randomly divided into group A(n=39)and group B (n =36).Patients in group A were treated with esomeprazole,amoxicillin and clavulanate potassium dispersible tablets,Clindamycin.Patients in group B were treated with omeprasole,amoxicillin and clavulanate potassium dispersible tablets,Clindamycin.Patients in both groups were treated with hypoglycemic therapy.The efficacy and the Hp eradicate rate of the two groups were observed and compared.Results The cure effect in group A was 97.44％(38/39),much better than that of group B(80.56％(29/36);x2=5.598,P=0.025).The Hp eradicate rate in group A was 92.31％,also much better than that of group B(75.00％;x2 =4.172,P =0.041).Conclusion The clinical egicacy and the Hp eradicate rate of esomeprazole triple therapies on gastric ulcer patients complicated with type 2 diabetes mellitus is better than that of omeprazole triple therapies.Esomeprazole triple therapies and it is worthy of being clinically promoted.
