Research progress of suppressor genes Fibulin-1 in tumor
10.3760/cma.j.issn.1673-4203.2015.10.019
- VernacularTitle:抑癌基因Fibulin-1在肿瘤中的研究进展
- Author:
Liang FENG
;
Wanjiang XUE
;
Qinsheng MAO
- Publication Type:Journal Article
- Keywords:
Fibulin-1;
Neoplasms;
Genes
- From:
International Journal of Surgery
2015;42(10):705-708
- CountryChina
- Language:Chinese
-
Abstract:
Fibulin-1 is a widely distributed,versatile secretory calcium-binding glycoprotein which plays an important role on the formation of the structure of the extracellular matrix,the regulation of intercellular signaling and the inhibition of cell motility.Recent studies suggested a tumor-suppressive role for Fibulin-1.Here,this review focuses on the expression,function and mechanism of Fibulin-1 genes in tumor.
