Predicting the response to neoadjuvant chemotherapy in gastric cancer
10.3760/cma.j.issn.1673-4203.2015.10.018
- VernacularTitle:胃癌新辅助化疗疗效预测方法及进展
- Author:
Yuanqiang DONG
;
Zhiming WANG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Drug therapy,combination;
Treatment outcome
- From:
International Journal of Surgery
2015;42(10):701-705
- CountryChina
- Language:Chinese
-
Abstract:
Randomized trials have demonstrated a benefit from neoadjuvant chemotherapy in gastric cancer.However the optimal approach in individual patients is not clear.There are differences in the chemical drug sensitivities of individual patients.This scenario demands the development of methods to predict response to neoadjuvant therapy.This paper reviews the relevant research progress.Published results are as follows:histological characteristics and histopathological response corelate with survival,traditional imaging needs improvement and integration to increase the accuracy,while PET holds advantage in early selection of patients without response,and existing candidate biomarkers need to bc properly qualified.
