Progress of tumor-associated macrophages as an therapeutic target against tumors
10.3760/cma.j.issn.1673-4203.2015.10.017
- VernacularTitle:以肿瘤相关巨噬细胞为靶点的抗肿瘤研究进展
- Author:
Weiping ZHU
;
Yiming ZHAO
;
Lu WANG
- Publication Type:Journal Article
- Keywords:
Macrophages;
Neoplasms;
Tumor microenvironment
- From:
International Journal of Surgery
2015;42(10):697-700
- CountryChina
- Language:Chinese
-
Abstract:
Tumor-associated macrophages (TAMs) exist in the tumor microenvironment,and can be affected by various anticancer treatments and further affect tumor progression.Increasing evidence suggests that many of the clinical antitumor measures can play a unique and effective antitumor effect by regulating the recruitment,polarization and related pro-tumor behavior of macrophages in the tumor microenvironment.Now,tumor microenvironment immune remodeling has become a hot spot in the research of anti-tumor therapy.This paper reviews the related research progress on antitumor effects of TAMs as an therapeutic target.
