Therapeutic effect of autologous stem cell transplantation of patients with cerebral hemorrhage sequelae under the stereotactic
10.3760/cma.j.issn.1008-6315.2015.05.001
- VernacularTitle:脑出血后遗症患者立体定向下自体干细胞移植的效果观察
- Author:
Hongyu REN
;
Mingliang LIU
;
Mingxuan LI
;
Jiangong MA
;
Cheng HE
- Publication Type:Journal Article
- Keywords:
Cerebral hemorrhage;
Sequelae;
Autologous stem cell;
Stereotactic
- From:
Clinical Medicine of China
2015;31(5):385-387
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effect of autologous stem cell transplantation research for patients with cerebral hemorrhage sequelae under the stereotactic.Methods One hundred patients with cerebral hemorrhage from Jan.2011 to Sep.2013 in our hospital were selected and randomly divided into the experimental group (n =50) and the control group (n =50).The patients of experimental group were given autologous stem cell transplantation under the stereotactic in 6 months after cerebral hemorrhage,while the patients in control group were just given traditional treatment.At 6,7 and 12 months after cerebral hemorrhage,rate with neural function defect scale and functional independence measure(FIM) scores of the two groups were compared.Results FIM scores in the experimental group was 102.08 ± 8.28,significant higher than that in control group(95.28±8.75,P＜0.05).Functional independence measure scores in the experimental group at 7 months after cerebral hemorrhage was 13.12±4.00,significant lower than that in control group(20.40±4.33,P ＜0.05).While,there was no statistical difference at 6 months and 12 months after cerebral hemorrhage between the two groups(P＞0.05).Conclusion The therapeutic of autologous stem cell transplantation on patients with cerebral hemorrhage sequelae under the stereotactic is benefit at short term,but the long term therapy effective still needs further study.
