Progress in non-hypersplenism factors of peripheral cytopenias in patients with portal hypertension
10.3760/cma.j.issn.1673-4203.2015.09.020
- VernacularTitle:门静脉高压性外周血细胞减少的非脾亢因素研究进展
- Author:
Jie DENG
;
Yunfu LYU
- Publication Type:Journal Article
- Keywords:
Portal hypertension;
Liver cirrhosis;
Peripheral blood cytopenias;
Non-hypersplenism factors;
Therapeutics
- From:
International Journal of Surgery
2015;42(9):639-642
- CountryChina
- Language:Chinese
-
Abstract:
The reduction of peripheral blood cells is a common and serious complication in hepatic cirrhosis portal hypertension patients with splenomegaly, and severely affects the prognosis.Its reasons include hypersplenism and non-hypersplenism factors.We should correctly understand these two factors.Hypersplenism factors is common, and non-hypersplenism factors, including the toxic effects of virus on the bone marrow, liver cirrhosis, hepatosis, immunodeficiency, the toxic effects of drugs, dystrophia, the destruction of platelets in blood circulation and hemorrhage.Etiological treatment and liver transplantation is the main treatment.Now, treatment of the reduction of peripheral blood cells has become an important topic.In this paper, the causes and treatments of peripheral blood cytopenias, which were caused by non-hypersplenism factors in the patients of liver cirrhosis and portal hypertension, were reviewed.
