Relationship between neutrophil to lymphocyte ratio and cardiovascular risk factors among community population
10.3969/j.issn.1008-0074.2015.05.02
- VernacularTitle:社区人群中性粒细胞／淋巴细胞比值与心血管病危险因素的关系
- Author:
Donghan ZHENG
;
Yuanzhe JIN
;
Zhiying DUAN
;
Yingzi LIN
;
Xueying ZHANG
;
Jingru WANG
;
Shuo HAN
;
Guofeng WANG
;
Yijing ZHANG
- Publication Type:Journal Article
- Keywords:
Lymphocytes;
Cardiovascular diseases;
Risk factors
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(5):476-480
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the relationship between neutrophil to lymphocyte ratio (N/L) and traditional cardio‐vascular risk factors among community 35~64‐year‐old residents .Methods :A total of 1884 residents (548 males and 1336 females) from urban Shenyang city received baseline condition questionnaire on cardiovascular diseases and re‐lated diseases from Apr 2011 to Feb 2012. According to presence of cardiovascular risk factors or not ,subjects were divided into healthy control group (n=675) and risk factor group (n=1209);according to number of risk factors , risk factor group was further divided into one risk factor group (n=491) ,two risk factors group (n=263) and ≥3 risk factors group (n=455) .Morning blood sample and urine sample were retained to measure blood and urine rou‐tine ,blood glucose and blood lipid profile etc in all subjects .N/L was compared and analyzed among all groups .Re‐sults:Among patients with only one of following risk factors [hypertension ,diabetes mellitus (DM) ,dyslipidemia and obesity] ,N/L levels of patients with hypertension or DM were significantly higher than that of healthy control group [1.55(1.15 ,1.95) ,1.60(1.21 ,2.07) vs .1.45(1.09 ,1.91)] , P<0.05 both ,and there were no significant difference between any other one risk factor group and healthy control group , P>0.05 all .Among risk factor sub‐groups ,N/L level of ≥3 risk factors group was significantly higher than that of two risk factors group [1.57(1.16 , 2.04) vs .1.41(1.07 ,1.89) ,P<0.05] ,and there was no significant difference between any other two groups (P>0.05) .Conclusion:N/L significantly related to hypertension or DM ,and N/L level of ≥3 risk factors group was sig‐nificantly higher than that of two risk factors group ,N/L is helpful to assess risk of cardiovascular diseases .
