Detection of the BDV specific CIC in plasma of patients with multiple sclerosis of Zunyi regions
- VernacularTitle:遵义地区多发性硬化患者血清BDV-CIC及抗体的检测
- Author:
Haijun LIU
;
Xiaoyan WU
;
Yongpan TIAN
;
Ping XU
- Publication Type:Journal Article
- Keywords:
BDV;
CIC;
ELISA;
multiple sclerosis
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(9):64-66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation with the infectious situation of Borna disease with the multiple sclerosisof Zunyi region. Methods Established method of the specific CIC and an antibody of Borna were used to detect the PBMC of 7cases of patients with multiple sclerosis and 93 cases of control group.Results In the collected 7 cases of PBMC in patients with multiple sclerosis, detected 2 positive samples of the specific CIC and antibody of Borna with a positive rate of 28.57%(2/7).Meanwhile, positive plasma samples were also detected in healthy control group, and the positive rate was 7.53%(7/93),The antibody positive rate of control group was also 5.38%(5/93).But between the two groups, the difference was no statistically significant.Conclusion Results indicate that the possibility of BDV infection is presented in Zunyi regions.BDV infection is not necessarily associated with multiple sclerosis.