Comparison of dezocine and fentanyl on immune status and serum levels of inflammatory cytokines of patients with breast cancer after surgery
- VernacularTitle:地佐辛与芬太尼对乳腺癌患者手术后免疫状况与血清炎性因子影响的对比研究
- Author:
Wenxin LI
;
Jincheng LI
- Publication Type:Journal Article
- Keywords:
analgesic solution;
breast cancer;
immune status;
inflammatory cytokines
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(9):76-78
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss comparison of different analgesic solution to the immune status and serum levels of inflammatory cytokines of the patients with breast cancer after surgery.Methods The patients of experimental group and control group were given Dizocine and fentanyl to analgesic respectively perioperative experimental.Then analysis and comparison the immune status and serum levels of the two groups.Results The T lymphocyte subsets ( The level of CD3 +、CD4 +and the ratio CD4 +/CD8 +) and the level fo NK cells of the exprimental group patients intraoperative and postoperative 1 d were significantly higer than the control group.The anti-inflammatory factor in the serum of the experimental group patients intraoperative and postoperative 1d was significantly higer than the control group.The proinflammatory factor in the serum of the experimental group patients intraoperative and postoperative 1 d was significantly lower than the control group.Conclusion Dizocine can significantly improve the serum inflammatory factors of the patients with brest cancer after surgery,and can adjust the patient’s immune status.
