Short-term effects of Aidi injection adjuvant GP methods chemotherapy in treatment for advanced non-small cell lung cancer
10.3969/j.issn.1000-484X.2015.10.022
- VernacularTitle:艾迪注射液辅助GP化疗方法对晚期非小细胞肺癌近期疗效评价
- Author:
Xiaoping CAI
;
Yuanhong JIN
;
Xiaoyu ZHU
;
Jiongwei PAN
;
Zhuo CAO
- Publication Type:Journal Article
- Keywords:
Aidi injection;
Chemotherapy;
Non-small cell lung cancer;
Immune function
- From:
Chinese Journal of Immunology
2015;(10):1397-1399
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the short-term effects,toxic side effects and immune function of Aidi injection adjuvant GP methods chemotherapy for advanced non-small cell lung cancer(NSCLC).Methods:130 patients with advanced NSCLC were divided into study group and the control group according to treatment methods.The study group were given Aidi injection +GP,and the control group only treated with GP.The short-term effects,toxic side effects gradeⅢ-Ⅳand immune function changes were compared between the two groups.Results:The overall response rate was 40.28%in study group,higher than 37.93% in control group(P>0.05).The two groups showed differences in the rates of leucocyte decrease,gastrointestinal reaction and platelets decrease(P<0.05).The levels of CD4,CD8 and CD4/CD8 didn′t changed obviously in study group(P>0.05),while in the control group the levels of CD4,CD8 and CD4/CD8 changed more significantly than before(P<0.05).The two groups also produced differences in CD4,CD8 and CD4/CD8 after treatment( P<0.05 ) .Conclusion: The short-term effects of Aidi injection adjuvant GP chemotherapy regimen for advanced NSCLC is similar to only GP chemotherapy,but it can obviously reduce the incidence of toxic side effects and prevent the immune func-tion.
