The Course of Brainstem Cavernous Malformations according to Management Strategies.
- Author:
Won Seok CHANG
1
;
Yong Sook PARK
;
Jong Hee CHANG
;
Dong Seok KIM
;
Seung Kon HUH
;
Yong Gou PARK
Author Information
1. Department of Neurosurgery, Yonsei University College of Medicine, Brain Research Institute, Seoul, Korea. yongsook@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Cavernous malformation;
Brainstem;
Radiosurgery;
Developmental venous anomaly
- MeSH:
Brain Stem*;
Follow-Up Studies;
Hemorrhage;
Humans;
Medulla Oblongata;
Mesencephalon;
Mortality;
Pons;
Radiosurgery
- From:Korean Journal of Cerebrovascular Surgery
2004;6(2):144-147
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The outcome and the rate of rebleeding of brainstem cavernous malformationss were analyzed following conservative treatment, microsurgical excision and Gamma Knife radiosurgery (GKS). We especially concentrated on the role of radiosurgery. We treated 39 patients with brainstem cavernous malformations using conservative treatment, microsurgical removal or GKS from April 1993 to November 2003. Follow up duration was 7 to 132 months (mean 45.8, median 30.6). The lesion location included pons, midbrain, medulla oblongata and cerebellarpeduncle. Conservative management was performed in 14 patients, GKS in 18 patients and microsurgical removal in 7 patients. The annual rate of rebleeding was 22.2% in conservative group and 22.7% in GKS group. Good and moderate outcome were obtained in 70% of conservative group, 75% of GKS group and 85.6% of surgical group. Overall mortality rate was 5.1%. Microsurgical excision tended to be resulted in good outcome. GKS and conservative managements were accompanied by a risk of recurrent bleeding, even death. There was no statistical difference in outcome and the rate of rebleeding between conservatively managed group and GKS treated group.
