Renal damage caused by Rhupus syndrome associated with anti-neutrophil cytoplas-mic antibodies vasculitis and cryoglobulinemia
10.3969/j.issn.1671-167X.2015.05.027
- VernacularTitle:Rhupus综合征合并抗中性粒细胞胞浆抗体及冷球蛋白血症引起的肾损害
- Author:
Xinju ZHAO
;
Tao WEI
;
Bao DONG
;
Yuan JIA
;
Mei WANG
- Publication Type:Journal Article
- Keywords:
Arthritis,rheumatoid;
Lupus erythematosus,systemic;
Cryoglobulinemia;
Kidney disea-ses;
Biopsy
- From:
Journal of Peking University(Health Sciences)
2015;(5):870-874
- CountryChina
- Language:Chinese
-
Abstract:
SUMMARY We analyzed the clinicopathological characteristics of one patient with Rhupus syndrome as-sociated nephropathy in Peking University People ’s Hospital, and reviewed the related literature .The pa-tient was a middle aged female .She developed rheumatoid arthritis first , and then manifested mild sys-temic lupus erythematosus together with positive anti-neutrophil cytoplasmic antibodies ( ANCA ) and cryoglobulinemia several years later .The renal biopsy was performed and manifested as lupus nephritis . The transmission electron microscopy revealed cryoglobulinemia associated renal damage .This report shows that the clinicopathological characteristics in patients with Rhupus syndrome associated nephropathy are complicated .The renal pathology can be used as a diagnostic tool .