Investigate the accuracy of real-time continuous glucose monitoring system in the type 2 diabetes subjects
10.11958/j.issn.0253-9896.2015.08.029
- VernacularTitle:探讨实时动态血糖监测在2型糖尿病患者中的准确性
- Author:
Chunfeng ZHANG
;
Huanqi GE
;
Yun XIE
;
Hui ZHENG
- Publication Type:Journal Article
- Keywords:
diabetes mellitus,type 2;
real-time continuous glucose monitoring;
accuracy;
error grid analysis
- From:
Tianjin Medical Journal
2015;(8):936-938
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the accuracy of real-time continuous glucose monitoring(RT-CGM)system in the type 2 diabetes mellitus(T2DM). Methods A total of 318 subjects hospitalized between 2013 May to 2014 August were recruited. Each subject received a RT-CGM system. In order to calibrate the interstitial glucose level, finger-stick blood glucose were measured at least four times every day. Patients were divided into three groups according to their finger-stick blood glucose level:≤6.99 mmol/L, 7.0-10.0 mmol/L and≥10.01 mmol/L. Pearson correlation was used to analyze the relationship between the finger-stick glucose and interstitial glucose gained from RT-CGM. Clarke error grid analysis was used to analyze the accuracy of RT-CGM. Results (1)A total of 2, 815 glucose meter values from finger-stick were com?paired with glucose from RT-CGM. A positive relationship(r=0.847)were found between CGM and finger-stick blood glu?cose. The correlation was closer with higher finger-stick blood glucose levels(r=0.457, 0.648 and 0.852 respectively in≤6.99 mmol/L group, 7.0-10.0 mmol/L group and≥10.01 mmol/L group. P<0.001).(2)The Clarke error grid analysis re?vealed that 76.69%of the readings from RT-CGM were clinical perfect (zone A), 20.28%were acceptable (zone B), 3.03%were unacceptable (zone C-E). Clinical perfect rate was lower when the finger-stick glucose≤6.99 mmol/L , compared with that when it is between 7.0-10.0 or≥10.01 mmol/L group(73.12%vs 78.63%&79.28%,P<0.05), there was no significant difference between group of 7.0-10.0 mmol/L with group≥10.01 mmol/L (P>0.05). Conclusion RT-CGM provides accu?rate blood glucose values to guide the treatment of diabetes, and the accuracy is more reliable in high glucose environment.
