Differences in lifestyle factors between functional constipation and constipation-predominant irritable bowel syndrome
10.3760/cma.j.issn.0254-1432.2015.07.010
- VernacularTitle:功能性便秘和便秘型肠易激综合征相关生活因素上的差异
- Author:
Chang LUO
;
Shangze LYU
;
Tao BAI
;
Xuelian XIANG
;
Xiaohua HOU
- Publication Type:Journal Article
- Keywords:
Functional constipation;
Constipation-predominant irritable bowel syndrome;
Lifestyle factors;
Logistic regression;
Decision trees
- From:
Chinese Journal of Digestion
2015;(7):460-464
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the differences of lifestyle factors between patients with functional constipation (FC)and constipation-predominant irritable bowel syndrome (IBS-C).Methods From February 2011 to December 2014,255 patients with chronic constipation were enrolled.Among them,there were 170 FC patients and 85 IBS-C patients.At the same period,170 healthy volunteers without symptoms of digestive diseases within one year were recruited as control.The data of demographic information and lifestyle factors were collected.First,single variant analysis was performed for statistical analysis and then the statistically significant variants were analyzed by multivariate logistic regression. Then the factors of FC and IBS-C patients were analyzed by decision tree model and the effects of factors under different categories were analyzed.Results The results of single variant analysis indicated that there was no difference in lifestyle factors between FC group and IBS-C group (all P >0.05).The results of multivariate logistic regression analysis showed that no independent protective or risk factors were found in IBS-C group compared with FC group.According to decision tree model analysis,body mass index (BMI),water intake per day and constipation family history were finally enrolled.The incidence of FC was higher in patients with BMI < 23.56 kg/m2 (except 18.74 to < 19.83 kg/m2 )(79.75 %).The incidence of FC was higher in patients with BMI from 18.74 to <19.83 kg/m2 and water intake <1 L
(66.67%).The incidence of FC was highest in patients with BMI≥23.56 kg/m2 and family history of constipation (70.00%).The total prediction accuracy of this model was 64.6% (42/65 )and area under curve (AUC)value was 0.688.Conclusions FC and IBS-C are related with many lifestyle factors.Low BMI and less water intake per day are influence factors of FC,while higher BMI and family history of constipation are influence factors of IBS-C.
