Biological markers of cerebral vasospasm after subarachnoid hemorrhage
10.3760/cma.j.issn.1673-4165.2015.06.009
- VernacularTitle:蛛网膜下腔出血后脑血管痉挛的生物学标记物
- Author:
Tao LYU
;
Xiaohua ZHANG
- Publication Type:Journal Article
- Keywords:
SubarachnoidHemorrhage;
Vasospasm,Intracranial;
BiologicalMarkers
- From:
International Journal of Cerebrovascular Diseases
2015;(6):469-473
- CountryChina
- Language:Chinese
-
Abstract:
Cerebralvasospasmisthemostcommonandmostdangerouscomplicationofsubarachnoid hemorrhage (SAH). If it can not be diagnosed and treated early, it w il result in delayed cerebral ischemia and delayed ischemic neurological deficits, and seriously affect the outcomes of patients. SAH can cause oxidative stress and inflammation, causing vasospasm, and leading to brain tissue damage. Numerous studies have show n that the concentrations and activities of numerous metabolites w il change in these pathological physiological processes. Identification of the changes of location, time and trend of these markers has important clinical significance for investigating the mechanism of cerebral vasospasm after SAH and seeking better therapeutic targets. This article review s the molecular markers of cerebral vasospasm after SAH.
