The biological characteristics and clinical significance of a novel heart failure marker：sST2
10.3760/cma.j.issn.1009-9158.2015.07.019
- VernacularTitle:新型心衰标志物sST2的生物学特征和临床意义
- Author:
Yamei XU
;
Junbo GE
- Publication Type:Journal Article
- Keywords:
sST2;
Cardiovascular disease;
BNP;
NT-proBNP
- From:
Chinese Journal of Laboratory Medicine
2015;(7):498-501
- CountryChina
- Language:Chinese
-
Abstract:
Soluble ST2 ( sST2 ) is protein of interleukin-1 ( IL-1 ) receptor family present in the blood which have been identified has the ability to capture IL-33, thereby inhibiting IL-33/ST2 signaling, the mechanical properties overload of myocardial cells was significantly increased .Thus, when at the onset of heart failure or chronic heart failure deteriorated , or at scarring resulted by myocardial infarction , soluble ST2 can be detected in the blood .The purpose of this review is to discuss the role of soluble ST 2 ( sST2) as a new cardiovascular marker.
