Mitogen-activated protein kinase signaling pathw ays and neuronal apoptosis after cerebral ischemia
10.3760/cma.j.issn.1673-4165.2015.06.008
- VernacularTitle:细胞内丝裂原活化蛋白激酶信号通路与脑缺血后神经元凋亡
- Author:
Jun XIE
;
Zhibo ZHANG
- Publication Type:Journal Article
- Keywords:
BrainIschemia;
p38Mitogen-ActivatedProteinKinases;
SignalTransduction;
MAP Kinase Signaling System;
Apoptosis
- From:
International Journal of Cerebrovascular Diseases
2015;(6):464-468
- CountryChina
- Language:Chinese
-
Abstract:
Cerebralischemiacaninducecelnecrosisincoreoftheinfarction,andapoptosisinthe ischemic penumbra. The mitogen-activated protein kinases (MAPKs) signaling pathw ays are activated after cerebral ischemia, causing programmed cel death, including apoptosis. This article review s the relationship betw een the MAPKs signaling family and neuronal apoptosis after cerebral ischemia.
