Progress of diagnostic criteria and treatment in systemic lupus erythematosus
10.3760/cma.j.issn.2095-428X.2015.13.006
- VernacularTitle:系统性红斑狼疮诊断标准及治疗进展
- Author:
Guimei GUO
;
Weixun HE
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus;
Lupus nephritis;
Diagnostic criteria;
Treatment;
Biological agent
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;(13):978-982
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus(SLE)is a common and complicated autoimmune disease. The Sys-temic Lupus International Collaborating Clinics Group undertook a revision of the American College of Rheumatology (ACR)classification criteria for SLE in 2009. The new revision included clinical criteria and immunogic criteria,and had greater sensitivity but lower specificity than ACR - 1997. Kidney Disease:Improving Global Outcomes(KDIGO) clinical practice guideline and ACR guideline elaborated the treatment for lupus nephritis. Children with lupus nephritis should receive the same therapies as adults with dosing based on patient size and glomerular filtration rate. Biological agents could be used to treat refractory SLE or those who were intolerant to traditional immunosuppressant.
