Mesenchymal stem cells-based cancer therapies
10.3760/cma.j.issn.1673-422X.2015.08.014
- VernacularTitle:间充质干细胞介导的肿瘤治疗
- Author:
Jie ZHANG
;
Lin FANG
;
Junnian ZHENG
- Publication Type:Journal Article
- Keywords:
Mesenchymal stem cells;
Neoplasms;
Vehicles
- From:
Journal of International Oncology
2015;(8):612-615
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells (MSCs)have inherent tumor-trophic migratory properties and low immunogenicity,which allow them to serve as vehicles for delivering effective,targeted therapy to tumors.MSC plays an anti-tumor role by releasing some cytokines,which can be strengthened by oncolytic virus,antiangio-genesis agent,tumor necrosis factor guided apoptosis ligand,IL,IFN and pro-drug.In addition,there are some advantages in combination treatment of MSC and others therapies.