Male breast cancer susceptibility genes
10.3760/cma.j.issn.1673-422X.2015.08.018
- VernacularTitle:男性乳腺癌的易感基因
- Author:
Xiaoqin HE
;
Yuanyuan GAN
;
Ximing XU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms,male;
Genes
- From:
Journal of International Oncology
2015;(8):625-627
- CountryChina
- Language:Chinese
-
Abstract:
Male breast cancer (MBC)is one of rare malignant carcinomas,of which the pathogenesis and biological characteristics remain elusive.Recently,it has been reported that breast cancer susceptibility gene (BRCA)1 ,BRCA2,checkpoint kinase 2 (CHEK2)and partner and localizer of BRCA2 (PALB2)play important roles in the pathogenesis of MBC.Whereas the relationship between BRCA1 -interacting protein 1 (BRIP1 )and MBC is still controversial.
