Effect of coenzyme complex on cardiac and renal functions of patients with type 2 cardiorenal syndrome
10.3969/j.issn.1006-5725.2015.16.019
- VernacularTitle:复合辅酶对2型心肾综合征患者心肾功能的影响
- Author:
Jia WANG
;
Ruofeng CHEN
;
Jianhao GUO
;
Liyao ZHOU
;
Zhujun TAN
;
Zhiliang LI
- Publication Type:Journal Article
- Keywords:
Type 2 cardiorenal syndrome;
Coenzyme complex;
Cardiac function;
Renal function
- From:
The Journal of Practical Medicine
2015;31(16):2648-2650
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of coenzyme complex on the cardiac and renal functions of patients with type 2 cardiorenal syndrome. Methods Sixty-two patients with type 2 cardiorenal syndrome were enrolled in from June 2013 to December 2014 in Zhujiang Hospital , Southern Medical University. These patients divided were into routine group (n = 31) and coenzyme complex (n = 31). The therapy scheme of coenzyme complex group was on the basis of routine group with coenzyme complex intravenous drip , 400 U/day for 2 weeks. The cardiac function was determined by New York Heart Function Assessment, and the cardiac ultrasound, the levels of BNP. The renal function was determined by serum creatinine and urine volume. Results Compared with routine group, the rates of NYHA Ⅲ and Ⅳ were reduced, the LVEF levels were increased and the levels of BNP were increased (P < 0.05). The serum creatinine was decreased and urine volume were increased in the coenzyme complex group (P<0.05). Conclusion Coenzyme complex could improve the cardiac and renal functions of the patients with type 2 cardiorenal syndrome.
