The incidence and the related factors of the depression in Parkinson's disease
10.3969/j.issn.1006-5725.2015.16.044
- VernacularTitle:帕金森病抑郁的发生率及相关因素分析
- Author:
Yu WU
;
Xiaoping PAN
;
Songran YANG
;
Yingjun OUYANG
;
Mengyan LI
;
Jianmin YU
;
Haobo CHEN
;
Ze LI
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Depression;
Non-motor symptoms;
Quality of life;
Related Factors
- From:
The Journal of Practical Medicine
2015;31(16):2717-2720
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence and the related factors of the depression in Parkinson's disease. Methods 52 cases with idiopathic Parkinson's disease were included in this study. Such scales as Hamilton depression scale-24 item (HAMD-24), Non Motor Symptoms Scale for Parkinson's disease (NMSS), 39-item Parkinson's Disease Questionnaire (PDQ-39), unified Parkinson's disease rating scale (UPDRS), revised Hoehn-Yahr rating scale (H-Y), revised Schwab and English daily life event scale (S-E), Minimum Mental State Examination (MMSE), etc. were applied and underwent Spearman correlation analysis. Results Thirty-six patients with Parkinson's disease (69.23%) met the criteria for depression. The spearman rank correlation analysis showed that MMSE (r=-0.294, P=0.036) and S-E (r=-0.506, P<0.001) had negative correlation with depression in Parkinson's disease, and the course of the disease (r=0.274, P=0.049), UPDRS (r=0.485, P<0.001), H-Y (r = 0.459, P = 0.001), NMSE (r = 0.729, P < 0.001) and PDQ-39 (r = 0.619, P < 0.001) had positive correlation with depression in Parkinson's disease. Conclusions The patients with Parkinson's disease had high incidence of depression. The depression in Parkinson's disease is associated with many factors and affected the quality of life of the patients.
