The levels of estradiol decline in the early luteal phase predictes the outcomes of in-vitro fertilization
10.3969/j.issn.1006-5725.2015.14.018
- VernacularTitle:黄体早期雌二醇下降幅度对体外受精-胚胎移植结局的预测
- Author:
Fan ZHANG
;
Jihong WEI
- Publication Type:Journal Article
- Keywords:
In vitro fertilization-embryo transfer;
Estradiol;
Early luteal phase;
Pregnancy rate
- From:
The Journal of Practical Medicine
2015;31(14):2300-2302
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of estradiol decline in the early luteal phase (the 2nd day after oocyte retrieval) in the prediction of in-vitro fertilization outcomes. Methods A total of 236 cases under in vitro fertilization-embryo transfer (IVF-ET)/ intracytoplasmic sperm injection-embryo transfer(ICSI-ET) cycles were included in this retrospective study of their medical records. The cases were divided into three groups according to the levels of estradiol decline on the 2nd day following OPU: group A (n = 70) with the decline rate of less than 70%, group B (n=114) with the decline rate of 70%~80%and group C (n=52) at the decline rate of more than 80%. The comparisons were done among the three groups in terms of the number of oocyte retrieval, the rate of fertilization, the rate of best oocytes and the rate of miscarriage. Results There were no significant differences statistically in the number of oocyte retrieval, the rate of fertilization, the rate of best oocytes and the rate of miscarriage (P > 0.05). But the rates of clinical pregnancy rate in groups A and B were significantly higher than that in group C (68.6% and 68.4% vs. 44.2%) (P < 0.05). Conclusion The levels of estradiol declines in the early luteal phase may be important in the prediction of IVF outcomes.
