Translational research on oral cancer:the current status and con-templation
10.3969/j.issn.1000-8179.2015.16.866
- VernacularTitle:口腔癌的转化医学研究现状与思考
- Author:
Zhiyuan ZHANG
- Publication Type:Journal Article
- Keywords:
oral cancer;
translational research;
random clinical trials;
biomarker
- From:
Chinese Journal of Clinical Oncology
2015;42(16):783-786
- CountryChina
- Language:Chinese
-
Abstract:
China has the largest human biological and pathological tissue resource in terms of both quantity and diversity, whichis true for oral cancer as well. However, this unique and valuable resource did not yield expected results in clinical translational research.On one side, clinicians lack experience in identification of research topics, even with plenty of clinical specimens. On the otherside, researchers consider high impact publications as the top priority instead of clinical significance. The disalignment of the interestsbetween these two sides led to inefficient and inadequate communications and collaborations. To change the current situation, we needto encourage clinicians to raise questions and generate research topics from clinical practice and to actively participate in translationalresearch. Meanwhile, researchers need to understand basics of clinical medicine and design research projects with a focus on clinicalproblems. Closer collaborations between clinicians and researchers will help to identify new biomarkers of clinical significance throughsystematic clinical studies, which have the potential to translate into practical knowledge in diagnosis, treatment and prognosis of diseases.We can further evaluate and validate these translational results systematically by large-scale random clinical trials.
