One case report of autoantibody-associated congenital heart block
10.3969/j.issn.1000-3606.2015.10.010
- VernacularTitle:自身抗体相关性先天性心脏传导阻滞1例报告
- Author:
Zongtai FENG
;
Xiaolu YANG
;
Zuming YANG
;
Yan CAI
;
Sannan WANG
- Publication Type:Journal Article
- Keywords:
autoantibody-related congenital heart block;
anti-SSA/Ro antibodies;
anti-SSB/La antibodies;
child
- From:
Journal of Clinical Pediatrics
2015;(10):880-882
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the pathogenesis, clinical manifestations, diagnosis, and treatment of autoanti-body-associated congenital heart block.MethodsThe clinical data of one child with autoantibody-associated congenital heart block was retrospectively analyzed.ResultsIn 24 week gestation, fetal bradycardia had been found by routine fetal echocar-diography. After birth, the anti-SSA/Ro antibodies and anti-SSB/La antibodies were positive in both infant and her mother. The diagnosis of autoantibody-associated congenital heart block was conifrmed. Intravenous immunoglobulin at 1 g/kg was adminis-trated. At 6 months follow-up, the electrocardiogram suggested type I second degree atrioventricular block.ConclusionIn the fetus or neonates found to have bradycardia and excluded the cardiac structural abnormalities, the autoimmune antibody should been tested and early intervention should been promoted.
