Intra-articular injection of synovial mesenchymal stem cells to treat articular cartilage injury
10.3969/j.issn.2095-4344.2015.36.027
- VernacularTitle:滑膜间充质干细胞关节腔内注射治疗关节软骨损伤
- Author:
Xiaolong YUAN
;
Shengrong BI
;
Fangyuan YU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2015;(36):5892-5897
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Among various seed cel s, synovial mesenchymal stem cel s have unique advantages in the repair of articular cartilage injury. OBJECTIVE:To review the progress of synovial mesenchymal stem cel s and its intra-articular injection in the treatment of articular cartilage injury. METHODS:The first author searched PubMed and CNKI by computer to retrieve articles published from January 2004 to December 2004 using the keywords of“synovial mesenchymal stem cel s;intra-articular injection;cartilage repair”in English and Chinese, respectively. Final y, 57 articles were included in result analysis. RESULTS AND CONCLUSION:It is easy to isolate and culture synovial mesenchymal stem cel s, which has great advantages in cartilage repair. What’s more, intra-articular injection therapy for articular cartilage injury is feasible and safe. Intra-articular injection of synovial mesenchymal stem cel s is a very promising treatment for cartilage damage, but there are stil many problems to be solved in the future.