Research progress of long non-coding RNA in regulating cell apoptosis and autophagy
10.3969/j.issn.1000-4718.2015.08.032
- VernacularTitle:长链非编码 RNA 调控细胞凋亡及自噬的研究进展
- Author:
Jing XU
;
Qiulin XU
;
Xiaohua GUO
- Publication Type:Journal Article
- Keywords:
Long non-coding RNA;
Apoptosis;
Autophagy;
Neoplasms
- From:
Chinese Journal of Pathophysiology
2015;(8):1525-1530
- CountryChina
- Language:Chinese
-
Abstract:
Longnon-codingRNAs(lncRNAs)areagroupofRNAslongerthan200bpwithoutprotein-coding capacity and play an important role in epigenetics , transcription regulation and post-transcription regulation .Recently, studies have shown that dysregulation of lncRNAs caused cell cycle disorders , and abnormal activities of cell apoptosis and autophagy , contributing to a variety of diseases .Therefore , the role of lncRNAs in regulating cell death is expected to lead to the discovery of potential novel diagnostic markers and therapeutic targets .
