Optimize the extraction process of Qingrejiedu oral liquid by multi-index comprehensive evaluation
- VernacularTitle:多指标综合评分法优选清热解毒口服液的提取工艺
- Author:
Tianshu GAO
;
Huili WANG
;
Yihong ZHAO
- Publication Type:Journal Article
- Keywords:
multi-index comprehensive evaluation;
Qingrejiedu oral liquid;
orthogonal test;
extraction process
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;37(7):141-144
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction techique for Qingrejiedu oral liquid.Methods The amount of water, extraction time , extraction times and alcohol content were used as inspection factor, 3 levels per factor, with baicalin, chlorogenic acid , geniposide transfer rate and extraction rate as indexes,carries on Weighted comprehensive evaluation,the optimal extractin were screened by L9 (34 ) orthogonal test.ResuIts The optimal extraction condition of Qingrejiedu oral liquid were as follow:extraction for 3 times and 1h each time with 8-fold amount of water and 70% alcohol. ConcIusion Through the orthogonal test, the extraction process of Qingrejiedu oral liquid is designed reasonably, the result is reliable, and the extraction effect is good, and has higher application value.
