A review of abuse-deterrent opioids
- VernacularTitle:阿片类药物的防滥用综述
- Author:
Jie WANG
;
Jun LI
;
Xinyi SU
;
Jun HAN
- Publication Type:Journal Article
- Keywords:
opioids;
addiction;
abuse-deterrent;
formulations;
mechanism
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;37(7):178-181
- CountryChina
- Language:Chinese
-
Abstract:
People departure from the treatment, prevention and health care purposes, intermittently or continuously excessive use of drugs with dependence, will cause serious mental and physical damage, while serious social harm.Opioids are the most commonly abused drug, abusers by taking an excess number of pills orally or by crushing the pills, followed by smoking, snorting, or injecting the new altered formulation to get euphoric.The escalating abuse of opioids has recently spawned the development of novel drug formulations resistant to various methods of tampering and misuse.This article discusses available opioids that include abuse-deterrent mechanisms as well as such agents currently in development.