Application of microsphere delivery system in treatment of osteoarthritis
- VernacularTitle:微球给药系统在骨性关节炎治疗中的应用
- Author:
Xiaojun XIA
;
Zhenlei YANG
;
Junli JING
- Publication Type:Journal Article
- Keywords:
osteoarthritis;
pathogenesis;
articular injection;
microspheres;
progress
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;37(7):185-188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the pathogenesis of osteoarthritis ( OA) and microsphere delivery systems advances in the field of osteoarthritis treatment, and provide theoretical support for clinical research and osteoarthritis therapy.Methods The literatures on osteoarthritis have been reviewed in recent years, and pathogenesis and osteoarthritis therapy were summarized.ResuIts At present, the therapy of OA was gradually from symptoms relief to pathogenesis, and further revealed the inner regularity of osteoarthritis treatment.However, a variety of western medicines had its own limitations. ConcIusion In recent years, intra-articular injection therapy because of its unique advantages in clinical treatments,attracts widespread attention, and particularly the microsphere injection with superior prospects is researched more in the field of new formulations.
